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Bortenat 3.5mg – Anticancer drugs | view uses, side effects and price | MHP
Bortenat 3.5mg | Bortenat 3.5mg injection | Bortenat 3.5mg injection Price in India
BORTENAT 3.5MG
DESCRIPTION
Bortezomib is sold under the brand name Bortenat 3.5mg which is a type of anti-cancer medicine, which is in the form of lyophilized powder A first beneficial proteasome inhibitor is known as Bortenat 3.5mg ; proteasome is a cellular structure which breaks the proteins.
Bortenat 3.5mg injection will helps to prevent from multiple myeloma in patients with or without before treatment history and mantle cell lymphoma.
INDICATION
Multiple myeloma Bortenat 3.5mg is indicated to treat the patients suffering from multiple myeloma. Mantle cell lymphoma Bortenat 3.5mg Injection is indicated to treat the disease mantle cell lymphoma which the patients have received at least 1 prior therapy.
MECHANISM OF ACTION
Bortenat 3.5mg injection used in mammalian cells is a reversible inhibitor of the chymotrypsin-like activity of the 26-S proteasome. The drug prohibits targeted proteolysis that affects multiple signaling cascades responsible for normal homeostatic functions within the cell, leading to cell death.
PRODUCT DETAILS
Brand : Bortenat
Ingredients : Bortezomib
Strength : 3.5mg vial
Manufactured : Natco
Package :3.5mg Bortezomib containing vial in a carton
ADME PROPERTIES
METABOLISM
Bortenat 3.5mg injection metabolized mainly through cytochrome P450 isoenzymes CYP3A4, CYP2C19 & CYP1A2.
DOSAGE MANAGEMENT
BORTENAT 3.5MG DOSAGE AND ADMINISTRATION
Bortenat 3.5mg is administrated alone or combination with dexamethasone Three week course is considered as therapy cycle Atleast 72 hours must slip away between constant doses of Bortenat.
MANTLE CELL LYMPHOMA
The Bortenat 3.5mg recommended dose for untreated mantle cell lymphoma is;1.3mg/m2 of Bortenatadministered as IV bolus given as two times weekly by combining with rituximab, cyclophospahmide, doxorubicin and tablet prednisolone for two weeks (day I, IV, VIII & XI) followed rest period of 10 days (day II through 21).
MULTIPLE MYELOMA
In the therapy of previously untreated multiple myeloma:1.3mg/m2 of dose must be given as 3 to 5 seconds through IV bolus or subcutaneous by concomitant use with tablet melphalan and prednisolone for nine 6 weeks therapy cycles Cycles 1 over 4, Bortenat 3.5mg is administrated for two times weekly, (day 1, 4, 8, 11, 22, 25, 29 and 32) Cycles 5 over 9, Bortenat is administrated once a week (day 1, 8, 22, and 29.
PRECAUTIONS
While taking Bortenat 3.5mg some adverse effects occurs care should be taken in the conditions like Bortenat 3.5mg leads to peripheral neuropathy like burning sensation, hyperesthesia, hypoesthesia, paresthesia, neuropathic pain Manage postural Hypotension by altering the antihypertensive agents, hydration, and administration of mineralocorticoids
PREGNANCY & LACTATION:
Bortenat 3.5mg is not recommended in pregnancy condition, it causes harm to fetus Breast feeding is not recommended.
STORAGE :
Bortenat 3.5mg vial should be stored at 20°C to 25°C (68°F to 77°F) excursion between 15°C to 30°C (59°F to 86°F). Keep away from light and heat.
MISSED DOSE:
If a single dose missed then administer the dose as you remember, If it is near to next dose then skip the missed dose and follow the regular schedule. Do not take extra dose at a time. Consult with the doctor for further changes in dose.
CONTACTS DETAILS
Email : millionhealthpharmaceuticals@gmail.com
Phone Number : +91-9940472902
Website : https://millionpharma.com/bortenat-3.5mg.php
Erlonat 150 mg – Erlotinib Natco tablet Price, Cost India.
Erlonat | Erlonat 150mg | Erlonat 150mg Price in India
Erlonat 150mg
Drug profile
Erlonat is a Natco pharma item which is containing a functioning substance known as Erlotinib, a first line medication of decision in metastatic phase of non little cell lung tumor.
Erlonat 150mg is normally endorsed for the patients who are not counters to less than one chemotherapy regimen.
Erlonat is pharmacologically arranged as tyrosine kinase inhibitor.
Erlonat 150mg is altogether raising the serum aminotransferase levels amid the treatment and this may causes liver wounds.
Erlonat 150mg tablets are containing 150mg of Erlotinib as a hostile to tumor specialist.
PRODUCT DETAILS
Brand name: Erlonat
Active constituent: Erlotinib
Strength: 150MG
Mfg: Natco pharma
Pack: 30 tablets per container
Category: Anti-neoplastic agent
Prescribing information of Erlonat ;
Before starting therapy with Erlonat 150mg, determination of mutation status is necessary for the patients to prevent the conditions like false positive or negative assessment.
Non small cell lung cancer:
Erlonat tablets are indicated primarily for the treatment of advanced NSCLC, in patients who are containing exon 19 deletions or 21substitution mutations.
Erlonat 150mg tablets are also considered as monotherapy for the advanced NSCLC patients who are progressive after 4 weeks of therapy with platinum based compounds.
Erlonat is mainly indicated for the patients who are not responding for one chemotherapy drugs.
But the potency of Erlonat 150mg has not been evaluated, for first line treatment in advanced NSCLC exon 19 deletions or mutations.
Mechanism of Erlonat
Erlonat has Erlotinib dynamic substance comprising hostile to neoplastic action with tyrosine kinase denying impact.
Erlonat 150mg displays hostile to tumor action by following up on cell surface in which the EGFR presents.
Erlonat mediates with EGFR phosphorylation which is brings about cell lyses.
Erlonat is likewise engaged with blockage of EFGR related flag exchange which is contributed for cell development.
Absorption
Nearly 60% of Erlotinib get absorbed after oral administration of Erlonat 150mg tablets.
The oral bioavailability reaches nearly 100%
In case of co administration of Erlonat tablets with gastric regulators like proton pump inhibitors causes depletion of Erlotinib exposure and leads to increase its concentration.
Distribution
Approximately 93% of Erlotinib get binds to human plasma protein.
Excretion
The mean creatinine clearance value 4.47L/hr
When to take the Erlonat 150mg tablets
Erlonat tablets should be administered on an empty stomach; it should be taken at least 1 hour earlier or 2 hours after food intake.
If patients not getting severe rashes, then therapy with Erlonat should be continue.
In combinational therapy of Erlonat 150mg with CYP3A4 substrates or modulators, dosage alteration is necessary for up to 50mg.
Dose modification;
In pulmonary symptoms like cough, dyspnea, fever conditions; Erlonat 150mg tablets treatment should be postpones.
In case of dose reduction is required for the patients, Erlonat dose may reduced to 50mg
Erlonat caused side effects
The most common adverse effects occurred in this therapy such as;
Severe diarrhea
Rashes
Interstitial lung disease
In NSCLC:
Anorexia
Fatigue
Dry skin
Conjunctivitis
Drug -drug interaction
Erlotinib should not be combined with platinum based compounds; it may increases the effect of concentration of platinum based compounds.
Erlonat 150mg should not be concomitant with Capecitabine; it may causes elevation of effect of concentration of Erlotinib.
Proteasome prohibitor like Bortezomib may be conventionally significant the effect of EFGR inhibitors including Erlonat
Erlonat tablets are strong inhibitor of CYP1A1, moderate inhibitor of CYP3A4 & CYP2C8 and also potent inhibitor of Glucuronidation by UGT1A1.
Erlonat tablet co administered with CYP3A4 inducers like rifampicin causes decreasing the exposure of Erlonat . Some CYP3A4 inducers like rifabutin, rifapentine, anti-convulsants.
Cigarette smoking is occurs during the therapy with Erlonat 150mg , leads to decreasing the exposure to Erlonat 150mg.
Erlonat solubility is occurs by pH values, once pH decreases solubility of Erlotinib get increases and causes loss of effects.
Erlonat should not be co administered with gastric regulators at a time; some time intervals like around 2 hours should be taken before or after ingestion of food.
Food drug interaction
Erlonat 150mg tablets should be taken on an empty stomach; because pH regulates the solubility of Erlotinib.
Possible contraindications
Any anaphylactic reactions like rashes, Stevens Johnson syndrome may occur during the therapy due to the patients are contraindicated to the component of Erlonat .
Safety measures
Interstitial lung disease may occur to overcome this effect by interrupt or discontinue the treatment with Erlonat .
Patient may frequently examine by undergone ILD analysis; this may occur in combinational therapy with gemcitabine.
In severity, discontinue the therapy with Erlonat 150mg.
5.GI perforations:
This may occur due to concurrent use of Erlonat with NSAIDS, corticosteroids, anti-angiogenic agents, or taxane based compounds causes GI perforation by increasing the acid levels in stomach.
7.Cardiac disorders:
Myocardial infarction may occur due to combination of Erlonat with gemcitabine, to avoid this problem stop the combinational therapy.
Pregnancy and lactation
Pregnancy category D
Erlotinib Erlonat 150mg causes fetal harm; it should not be suggested in pregnancy condition.
Breast feeding should not be allowed.
Storage and handling
Erlonat 150mg tablet container should be stored at 25oC.
The container should be keep away from heat, light & moisture.
Over dosage
Missed dose is the one of the reason for obtaining over dosage condition.
Once over dosage of Erlonat occurs in patients, must provided with supportive measures and follow the preventive measures
The over dosage of Erlotinib causes severe diarrhea & rashes, elevating AST, ALT leads to liver damage.
Discontinue the therapy.
CONTACT DETAILS
Million Health Pharmaceuticals
Old.No.131,New.No.50,Pedariyar kovil street
Seven wells,Chennai-600001.Tamilnadu,India
email : millionhealthpharmaceuticals@gmail.com
Trending Keywords : Erlonat | Erlonat 150mg | Erlonat 150mg Price in India
Business Process Management Company in Chennai – Apple Infoway
BUSINESS PROCESS MANAGEMENT
BUSINESS PROCESS MANAGEMENT COMPANY IN CHENNAI
The BPM company in chennai is about the people to utilize the model, introduces the schemes and abundance of project takes place by the clients. It manages the help of automation. The Business process repercussion the lack of awareness takes place in the business. The process, which takes place as edits, analyzes the predictable process. The business takes place by the team and HR in the company and by the clients. It has more controversies in the team works the management in the business would be motivated. In the business process, the company has different place take place, it has data, raw materials and processing. The management should lead the company different handles.
It can be handled by the different department and the processing of management should be effective and efficient organization. The business takes place to improve the knowledge and by the team work. The company takes place an individual process and sets back the things. It can handle through by the techniques. It is a different scenario, executing and improving the skills, monitoring the improved process and optimizes it.
The tool which has been used in BPM company in chennai is model, implement and automatic business workflow and goal of improving corporate performance, miscommunication and inefficiency.Task management is about handling or organizing a set of activities that arise out of a project. These projects are often one-time and non-repeatable. When these projects are well-organized like in construction work, project management software like ‘Microsoft Project’ is used.At the individual level, people only see one part of a process, and very few can scan out and see the full effects of a process, where it starts and ends, the key data needed, and where potential bottlenecks and inefficiencies lie.
STEPS FOLLOWED IN BPM :
The Business Process steps taking place are,
• Monitor
• Design
• Model
• Execute
• Optimize
The various business management processesthattakes place in the process are INTEGRATION CENTRIC, DOCUMENT CENTRIC, HUMAN CENTRIC. The incorporate business process takes placeby the chaotic level, individual level and to create, analyze, map the structure. The process runs through the individuality level of the management. And improve optimize the level of management. The teams should understand the bigger organizational goal. It has the digital transformation. It has a tangled option. In the process, it has different steps that is routing, formatting, and verifying the documents.
In the business process the team has different works; they are HR, sales, teams. Every individual has the work to complete the process. The HR department has to enact the every candidate and fill the paper work, ask to finish the project on time. They have to act in the organization in end to end game, cost, time of the team work. HR process is to make the organization in the best way.
Then the sales department takes place in business process management, it has invoice process, one and fourth of workers. The people should manage the tools of company in the sales departments. In the sales department has invoice and be a short time process. There is a varied diversity of business management process takes place in the company. It attributes the discipline of capability.
Then the Financial departments are take place in the business process should the paper forms, emails everyday process. It is the daily basis of the scenario. It should transform the paper forms and emails in various teams. It is the daily process. It is the confirm place and unique scenario of the everyday places. The financial department has the one takes part in everyday works. It has been customize unique workflow.
In the process management system has visualizing the tools, diagramming the tool process and also it has examining the techniques takes place in the business. It also works in the mobile support, power admiring support. Performance of large user bases are takes place in the process and also Drag and designer are used in the process.
It has typically includes in the business rule management, capability to integrate with external system, communication management, end-user environment and then chart and analytics. In the business management of technology level is above.
BPM company in chennai is the possible organization to streamed the complex process of timing and efficient way. It is best place to improve the processing the platform level and workflow of the company. The business management is the software process, and packing the things in the email way. The accomplishment and achievement of these goals and objectives require the performance of a task or activity, or a series of tasks and activities. These sets of activities or tasks, which are logically related and often follow a logical flow, are referred to as business processes.
It is an article to managing the task in the Business process management. It organizing the outcome and paper forms of the company and it has task to complete the process. It is study, identify, and monitor the process in the system level of the process. It enabling the process and assigning the process, it generally means that “workflow”.
BPM company in chennai is the one time process and continuous over flow of the project in action. The action takes place in the BPM company in chennai is that managing the role of project and building the incorporated the workflows of company rule.
The BPM is extended and incorporated the workflow of the company process. The management should enable the teams and clients in the good manner and it should execute in the proper way. It implementing the process and managing the things in projects. The success of implementing the process is to be a large measure of the projects. The environment of the business process is modifying the data, tools, platforms.
BPM is the only process to improve the software packages of the IT companies. It enables through the Email process. It has the techniques to work in the company. The Business management knows the truth to improve the skills of the process level and the leads the company by the rule. The managing the process is to workflow of productivity and improve the flexibility process. In the BPM not only designers process it has many management in the business process.
The level of managing the system is to be team work and the clients should be good to the teams and enable the process levels. In the Business process mobile workforce also takes place in the company in the overall organizational goals. It standardizing the workflow of business and set a procedures.
A process is simply a set of activities carried out together for a purpose. In most cases, we follow a process to get something done consistently each time we need to complete the task. For example, every morning you wake up and get ready to go where you need to go. Many of us carry out the same routine every morning. Our processes will vary from person to person, but common morning processes consist of taking a shower, getting dress, and eating breakfast. We carry out these same activities almost every morning for the purpose of getting to where we need to be, whether that is work or class.
By concluding the Business Process Management, there are many tools, data’s, and monitoring the system. It takes place by the procedures, it generally mean that the “workflow” process. It improves the flexibility of the business and enables the processing level of management.
CONTACT DETAILS
Email : Appleinfoways@Gmail.Com
Phone Number : +91 – 90873 22777 , +91 – 93800 37777
website : https://appleinfoway.com/business-process-management.php
BeemaInfratech – Aluminium Scaffolding Dealers in Chennai
OUR PRODUCTS
Reckoned as one of the emergent companies of the industry, we are extremely immersed in manufacturing an inclusive range of Scaffold Ladder, Tower Ladder, Step Ladder, Aluminium Ladder, FRP Ladder and aluminium scaffolding dealers in chennai. Our whole range of products is provided with quality declaration.
ALUMINIUM LADDER
Manufacturer of a wide range of products which include self support extension ladder, aluminum ladder, aluminum extension ladder, wall support extendable ladder, wall supporting straight ladder,aluminium folding ladder and aluminium scaffolding dealers in chennai.
SCAFFOLD LADDER
Leading Manufacturer of aluminium double width scaffold ladder, aluminium scaffold ladder, combination scaffold ladder, mobile scaffold tower, scaffold stair, scaffolding accessories and Aluminium scaffolding dealers in chennai.
TOWER LADDER
We bring forth our vast industrial experience and expertise in this business, instrumental in providing Aluminium Tiltable Tower Ladder.
STEP LADDER
Our product range includes a wide range of aluminium step ladder and arch step ladder.
CONTACT DETAILS
Email : info@beemainfratech.com
Phone Number : +91 9489004466, +91 9489004433,
Address : No. 24, K. M. A. Garden, Industrial Estate Chinandimadam Kodungaiyur, Chennai- 600118, Tamil Nadu, India.
Website : https://beemainfratech.com/
Glenza 40 mg (Glenmark)|Enzalutamide capsules-uses,dose,side effects,price India
Glenza 40mg | Glenza 40mg tablets | Glenza 40mg tablets Price in India.
GLENZA
DESCRIPTION
Enzalutamide is an active ingredient of glenza 40mg tablets available in the strength of 40mg. glenza 40mg tablets are used to treat the metastatic prostate cancer, in men. Glenza 40mg is exhibits its action by stopping the advancement of tumor cells by blockade of androgen hormones especially testosterone.
Glenza 40mg containing Enzalutamide is also categorized as an anti-androgen chemo medicine. Glenza 40mg is not self medication; it is used under the knowledge of medical oncologist.
GLENZA 40MG TABLETS USES
Glenza 40mg tablets are prescribing for; Metastatic or long lasting castration resistant prostate cancer
GLENZA 40MG TABLETS MECHANISM
Glenza 40mg containing anti-androgen agent like Enzalutamide, it expels an anti-tumor activity in different steps. Glenza 40mg tablets are interfere in androgen receptor signaling pathway, which prohibiting androgen binding to androgen receptors leads to androgen receptor nuclear translocation inhibition and interact with DNA. The major metabolite of Glenza 40mg is N-desmethyl Enzalutamide which is similar to Enzalutamide activity. The anti-tumor activity of Glenza 40mg is exposed by depleting the multiplication and persuades cell lysis in prostate cancer cells.
PRODUCTS DETAILS
Brand : Bdenza
Ingredients : Enzalutamide
Strength : 40mg
Manufactured : BDR pharmaceuticals
Package : 28 Tablets
ADME PROPERTIES
After an oral administration of Glenza 40mg tablets (160mg of dose), undergoes ADME process and exhibits activity. The peak plasma concentration time of Glenza 40mg occurs at 1 hour with the range of 0.5 to 3 hours). The steady state of Glenza 40mg occurs in day 28. The volume of distribution occur after single dose of Glenza is 110L Glenza 40mg tablets has highly bounds to the human plasma protein with the range of 97 to 98%.
Glenza 40mg is majorly excreted through liver metabolism, 71% of metabolite present in urine and 14% in feces. The terminal half life period of Glenza 40mg tablet is occurs after a single dose at 5.8days and N-desmethyl Enzalutamide is taken 7.8 to 8.6 days.
DOSAGE MANAGEMENT
The usual recommended dosage of Glenza is 160mg, but available strength of Glenza is 40mg. Four tablets of Glenza 40mg should be taken at a time as a single dose. Glenza 40mg tablet should be administered with or without food.
Dosing alteration: In ≥ grade 3 toxicity or extreme side effects: Postpone the dose of Glenza for 1 week or as far as symptoms progress to ≤ grade 2, continue at the same or reduced to 120mg or 80mg. Concurrent use with strong CYP2C8 inhibitors:
In case of combination with strong CYP2C8 inhibitors, diminish the dose of Glenza 40mg to 80mg as a single dose. Concurrent use with strong CYP3A4 inducers: In case of combination with strong CYP3A4 inducers, increasing the dose of Glenza 40mg tablets 160mg to 240mg as a single dose.
GLENZA 40MG TABLETS SAFETY PRECAUTIONS
The major adverse effect during the therapy of Glenza 40mg tablets are;
SEIZURE
Seizure may produce during the treatment with Glenza 40mg tablets, if seizure occurs the treatment should be discontinued until seizure resolved. To avoid this condition, patient should be counsel about the problems occurred during the therapy before starting the treatment. Seizure may leads to loss of consciousness.
POSTERIOR REVERSIBLE ENCEPHALOPATHY SYNDROME PRES
Patient who are all taking Glenza 40mg tablets acquired PRES, is a neurological problem produce symptoms like headache, lethargy, confusion, loss of vision, other neurological problems related with hypertension. PRES diagnosed by MRI. If patient acquired with PRES, discontinue the Glenza 40mg therapy
GLENZA 40MG TABLETS CAUSING SIDE EFFECTS
Asthenia
Peripheral edema
Hypertension
Headache
Dizziness
Spinal cord compression
Caude equine syndrome
Paresthesia
Mental disorders
PREGNANCY & LACTATION:
The pregnancy category of is X Glenza tablets are contraindicated to pregnancy conditions; it may cause fetal harm even to death. Glenza 40mg tablets are contraindicated in lactation period, breast feeding should not be recommended.
STORAGE :
The storage condition of Glenza 40mg tablets container at 20°C to 25°C (68°F to 77°F). Container should be kept at dry and cool place.
MISSED DOSE:
Glenza 40mg is a chemo tablets, if patient fail to take the dose of Glenza 40mg tablets must be consult with medical oncologist and take the dose within a time. In any other way the missed dose should be avoid and follow the regular dosing schedule.
CONTACT DETAILS
Email :millionhealthpharmaceuticals@gmail.com
Phone Number :+91-9940472902
Website : https://millionpharma.com/glenza.php
Trending Keyword : Glenza 40mg | Glenza 40mg tablets | Glenza 40mg tablets Price in India.
Bortenat 2mg – Anticancer drugs | view uses, side effects and price | MHP
Bortenat 2mg | Bortenat 2mg Injection | Bortenat 2mg Injection Price in India
BORTENAT 2MG
DESCRIPTION
Bortezomib is sold under the brand name Bortenat 2mg which is a type of anti-cancer medicine, which is in the form of lyophilized powder A first beneficial proteasome inhibitor is known as Bortenat 2mg Injection ; proteasome is a cellular structure which breaks the proteins.
Bortenat 2mg injection will helps to prevent from multiple myeloma in patients with or without before treatment history and mantle cell lymphoma.
INDICATION
Multiple myeloma Bortenat 2mg is indicated to treat the patients suffering from multiple myeloma. Mantle cell lymphoma Bortenat 2mg Injection is indicated to treat the disease mantle cell lymphoma which the patients have received at least 1 prior therapy.
MECHANISM OF ACTION
Bortenat 2mg injection used in mammalian cells is a reversible inhibitor of the chymotrypsin-like activity of the 26-S proteasome. The drug prohibits targeted proteolysis that affects multiple signaling cascades responsible for normal homeostatic functions within the cell, leading to cell death.
PRODUCT DETAILS
Brand : Bortenat
Ingredients : Bortezomib
Strength : 2mg vial
Manufactured : Natco
Package : 2mg Bortezomib containing vial in a carton
ADME PROPERTIES
ABSORPTION
The peak plasma concentration after 1st dose is 57 and 112ng/mL, If administrated two times a week, Cmax observed for 1mg/m2dose is 67 to 106ng/mL, for 1.3mg/m2 is 89 to 720ng/mL.
DISTRIBUTION
Human serum plasma concentration is >80%
METABOLISM
Bortenat 2mg injection metabolized mainly through cytochrome P450 isoenzymes CYP3A4, CYP2C19 & CYP1A2.
ELIMINATION
The excretion pathways of Bortenat 2mg have not been characterized. The terminal elimination of half life after the 1mg/m2 dose is 40hrs – 193hrs, after dose 1.3mg/m2 is 76hrs – 108hrs.
DOSAGE MANAGEMENT
BORTENAT 2MG DOSAGE AND ADMINISTRATION
Bortenat 2mg is administrated alone or combination with dexamethasone Three week course is considered as therapy cycle Atleast 72 hours must slip away between constant doses of Bortenat. Bortenat 2mg Injection (lyophilized powder form) is reconstituted by using 0.9% sodium chloride (NS)Bortenat should be reconstituted in 3.5ml NS The route of administration is IV bolus Intrathecal not use for administration In adults:MANTLE CELL LYMPHOMA
The Bortenat 2mg recommended dose for untreated mantle cell lymphoma is;1.3mg/m2 of Bortenat administered as IV bolus given as two times weekly by combining with rituximab, cyclophospahmide, doxorubicin and tablet prednisolone for two weeks (day I, IV, VIII & XI) followed rest period of 10 days (day II through 21). In Relapse stage: The normal dose of Bortenat is 1.3mg/m2 administered as IV bolus or subcutaneous two times for two weeks (day I, IV, VIII & XI) followed by 10 day rest period (day II through 21) The therapy should followed for above 8 cycles may be given for once weekly for 4 weeks (day 1, 8, 15 & 22), followed by 13 day rest (days 23 through 35)
MULTIPLE MYELOMA
In the therapy of previously untreated multiple myeloma:1.3mg/m2 of dose must be given as 3 to 5 seconds through IV bolus or subcutaneous by concomitant use with tablet melphalan and prednisolone for nine 6 weeks therapy cycles Cycles 1 over 4, Bortenat 2mg Injection is administrated for two times weekly, (day 1, 4, 8, 11, 22, 25, 29 and 32) Cycles 5 over 9, Bortenat is administrated once a week (day 1, 8, 22, and 29)KEY POINTS
Moderately, 72 hours should be passing between following doses of Bortenat 2mgIN RELAPSE STAGE
The usual dose of Bortenat 2mg is 1.3mg/m2 should be administered through IV bolus or subcutaneous as two times for two weeks (day1, 4, 8, and 11) continued by a ten day of rest course (day 12 through 21)
PRECAUTION
While taking Bortenat 2mg some adverse effects occurs care should be taken in the conditions like Bortenat 2mg injection leads to peripheral neuropathy like burning sensation, hyperesthesia, hypoesthesia, paresthesia, -stop the Bortenat 2mg therapy Gastrointestinal toxicity-fluid or electrolyte replacements have to take Thrombocytopenia and neutropenia Tumor lysis syndrome Hepatic toxicity Embryo fetal toxicity
SIDE EFFECTS
BORTENAT 2MG SIDE EFFECTS
MOST COMMON SIDE EFFECTS
Black tarry stools ; Bleeding gums ; Blood in urine ; Blurred vision ; Body aches ; Burning, crawling, itching, numbness, prickling ;Chest pain ; Cough producing mucus, dizziness, faintness, nerve pain, painful urination, pale skin, runny nose, sore throat, stuffy nose, swollen glands, sunken eyes, ulcer, dry mouth, ear congestion, loss of voice
PREGNANCY & LACTATION:
Bortenat 2mg is not recommended in pregnancy condition, it causes harm to fetus Breast feeding is not recommended.
STORAGE :
Bortenat 2mg vial should be stored at 20°C to 25°C (68°F to 77°F) excursion between 15°C to 30°C (59°F to 86°F). Keep away from light and heat.
MISSED DOSE:
If a single dose missed then administer the dose as you remember, If it is near to next dose then skip the missed dose and follow the regular schedule. Bortenat 2mg Do not take extra dose at a time. Consult with the doctor for further changes in dose.
CONTACTS DETAILS
Email : millionhealthpharmaceuticals@gmail.com
Phone Number : +91-9940472902
Webiste : https://millionpharma.com/bortenat-2mg.php
Trending Keywords : Bortenat 2mg | Bortenat 2mg Injection | Bortenat 2mg Injection Price in India .
Sorafenib Soranib 200mg – Anticancer drugs | Cipla | MHP
Soranib 200mg | Soranib 200mg tablet | Soranib 200mg tablet Price in India .
SORANIB
DESCRIPTION
Sorafenib sold under the brand name Soranib 200mg. Soranib 200mg Tablets belongs to the group of tyrosine kinase inhibitor or inhibitor of angiogensis. The drug is a type of targeted therapy Soranib 200mg is a prescription drug used under the supervision of health care provider.
INDICATION
Soranib 200mg Tablets is a anticancer drug and indicated for the treatment of some condition as Advanced renal cell carcinoma Hepatocellular carcinoma Metastatic thyroid carcinoma
DOSAGE
IN RENAL CELL CARCINOMA
The dose of Soranib 200mg is given as 400mg should be taken orally as twice daily for at least one hour before or two hours after the meal
THYROID CARCINOMA
The dose of Soranib 200mg Tablets is given as 400mg should be taken orally as twice daily for at least one hour before or two hours after the meal
HEPATOCELLULAR CARCINOMA
The usual dose of Soranib 200mg is given as 400mg should be taken orally as twice daily for at least one hour before or two hours after the meal.
SORAFENAT WORKS IN THE BODY
Soranib 200mg Tablets includes in deficiency of tumor cell multiplication Soranib 200mg interfere with multiple intracellular and cell surface kinase These enzymes are specific for tumor cell signaling, angiogenesis and apoptosis. Soranib 200mg causes to reduce the blood flow to the cancer cells By prohibiting these enzymes (kinase), genetic transcription includes in cell proliferation and angiogenesis is blocked.
DRUG INTERACTION
Interaction of Soranib 200mg Tablets with Rifampin a strong CYP3A4 inducer, administered at a dose of 600mg single use for 5 days with Soranib causes decrease AUC of Sorafenib 200mg Interaction with neomycin will reduce the AUC of Sorafenib 200mg Tablets Interaction with acetaminophen will raises the hepatoxicity effect of Sorafenib 200mg Interaction with Bevacizumab will increase the toxic effect of Sorafenib.
PRODUCTS DETAILS
Brand : Soranib
Ingredients : Sorafenib
Strength : 200mg
Manufactured : Cipla
Package : 120 Tablets
BODY WORKS FOR THE DRUG SORAFENIB
ABSORPTION
The Soranib 200mg Tablets bioavailability is 38 to 49% The time to peak serum concentration in 3 hours. High fat meals may decrease the bioavailability of Sorafenib 200mg
DISTRIBUTION
The drug Soranib 200mg tablets has Human plasma protein bound is 99.5%
METABOLISM
In liver Soranib 200mg is highly metabolized, it go through oxidative metabolism with the help of CYP3A4 and Glucuronidation by UGT1A9 The main flowing metabolite in serum is pyridine N oxide
ELIMINATION
The dose excreted via feces 77% The dose excreted via urine 19% as glucuronidated metabolites Soranib 200mg tablets half life is 25 to 48 hours
SAFETY PRECAUTIONS &
CONTRAINDICATION
Soranib 200mg should not be used, in case of lung cancer, being treated with platinum containing chemo drugs and taxol drugs Soranib 200mg Tablets able to cause heart problems, stop the medicine in case of dizziness, fainting, sweating or shortening of breath Soranib 200mg causes severe bleeding; care should be taken while getting Soranib 200mg Tablets Stop the Tablet Soranib 200mg in case of;
blood in urine or stools, blood while coughing, Vaginal bleeding Hemorrhage risk QT prolongation. High occurrence of skin toxicity and rashes. Impairs exogenous thyroid suppression. Hypersentivity to the drug and any product of expicients.
SIDE EFFECT
Lymphopenia Neutropenia Hemorrhage Hypertension Neuropathy Anorexia Headache Joint pain Congestive heart failure Acute renal failure Angiodema arrhythmia Interstitial lung disease Post marketing reports: Hypersensitivity reactions: angioedema, anaphylactic reaction Hepatobiliary disorders: hepatitis, hepatic failure and death Musculoskeletal: rhabdomyolysis, osteonecrosis of the jaw Pulmonary: interstitial lung disease
PREGNANCY
Category D: Soranib 200mg tablets can harm to an fetus and cause injury and even death to the unborn baby if you treatment during the 2nd and 3rd trimesters of pregnancy, pregnant women do not use the Soranib medicine without the knowledge of your doctor.
LACTATION
The medicine passes into breast milk is not known or could harm a new born baby. Do not use Soranib 200mg medication, if your breast feeding.
STORAGE
Soranib 200mg tablets should be store at 25°C (77°F); excursion are allowed between 15°C and 30oC (59°F and 86°F) Protect from moisture, heat and light
MISSED DOSE
If patient missed to take Soranib 200mg tablet, they may get advice from medical practitioner (consult) for administration of the missed dose within the time Or the missed dose should be skipped and follow the next dosing schedule Do not have double the dose.
CONTACT DETAILS
Email : millionhealthpharmaceuticals@gmail.com
Phone Number : +91-9940472902
Trending Keyword : Soranib 200mg | Soranib 200mg tablet | Soranib 200mg tablet Price in India .
Website : https://millionpharma.com/soranib.php
Velcade 3.5 mg Injection – Uses, Dosage, Side Effects, Price, Composition|MHP
VELCADE 3.5MG
DESCRIPTION
Bortezomib is sold under the brand name Velcade 3.5mg which is a type of anti-cancer medicine, which is in the form of lyophilized powder
A first beneficial proteasome inhibitor is known as Velcade 1mg; proteasome is a cellular structure which breaks the proteins.
Velcade 3.5mg injection will helps to prevent from multiple myeloma in patients with or without before treatment history and mantle cell lymphoma.
INDICATION
Multiple myeloma :
Velcade 3.5mg is indicated to treat the patients suffering from multiple myeloma.
Mantle cell lymphoma :
Velcade 3.5mg is indicated to treat the disease mantle cell lymphoma which the patients have received at least 1 prior therapy.
MECHANISM OF ACTION
Velcade 3.5mg injection used in mammalian cells is a reversible inhibitor of the chymotrypsin-like activity of the 26-S proteasome. The drug prohibits targeted proteolysis that affects multiple signaling cascades responsible for normal homeostatic functions within the cell, leading to cell death.
PRODUCTS DETAILS
Brand : Velcade
Ingredients : Bortezomib
Strength : 3.5mg vial
Manufactured : Janssen Pharmaceuticals
Pack : 3.5mg Bortezomib containing vial in a carton
PHARMACOKINETIC
ABSORPTION
The peak plasma concentration after 1st dose is 57 and 112ng/mL, Ifadministrated two times a week, Cmax observed for 1mg/m2dose is 67 to 106ng/mL, for 1.3mg/m2 is 89 to 720ng/mL.
DISTRIBUTION
human serum plasma concentration is >80%
METABOLISM
Velcade 1mg injection metabolized mainly through cytochrome P450 isoenzymes CYP3A4, CYP2C19 & CYP1A2.
ELIMINATION
The excretion pathways of Velcade have not been characterized.
The terminal elimination of half-life after the 1mg/m2 dose is 40hrs – 193hrs, after dose 1.3mg/m2 is 76hrs – 108hrs.
DOSAGE MANAGEMENT
DOSAGE AND ADMINISTRATION
Velcade is administrated alone or combination with dexamethasone
Three-week course is considered as therapy cycle
At least 72 hours must slip away between constant doses of Velcade
• Velcade (lyophilized powder form) is reconstituted by using 0.9% sodium chloride (NS)
• Velcade should be reconstituted in 3.5ml NS
• The route of administration is IV bolus
• Intrathecal not use for administration
In adults:
MANTLE CELL LYMPHOMA
The Velcade 3.5mg recommended dose for untreated mantle cell lymphoma is;1.3mg/m2 of Velcade administered as IV bolus given as two times weekly by combining with rituximab, cyclophosphamide, doxorubicin and tablet prednisolone for two weeks (day I, IV, VIII & XI) followed rest period of 10 days (day II through 21).
In Relapse stage:
The normal dose of Velcade is 1.3mg/m2 administered as IV bolus or subcutaneous two times for two weeks (day I, IV, VIII & XI) followed by 10-day rest period (day II through 21)The therapy should follow for above 8 cycles may be given for once weekly for 4 weeks (day 1, 8, 15 & 22), followed by 13 day rest (days 23 through 35)
MULTIPLE MYELOMA
In the therapy of previously untreated multiple myeloma:1.3mg/m2 of dose must be given as 3 to 5 seconds through IV bolus or subcutaneous by concomitant use with tablet melphalan and prednisolone for nine 6 weeks therapy cycles
Cycles 1 over 4, Velcade is administrated for two times weekly, (day 1, 4, 8, 11, 22, 25, 29 and 32)
Cycles 5 over 9, Velcade is administrated once a week (day 1, 8, 22, and 29)
KEY POINTS
Moderately, 72 hours should be passing between following doses of Velcade 3.5mg
IN RELAPSE STAGE
The usual dose of Velcade is 1.3mg/m2 should be administered through IV bolus or subcutaneous as two times for two weeks (day1, 4, 8, and 11) continued by a ten day of rest course (day 12 through 21) The schedule of the treatment has been raised above 8 cycles may be taken once weekly for 4 weeks (day 1, 8, 15, and 22), followed by 13 day rest (day 23 over 35)
While taking Velcade 3.5mg some adverse effects occurs care should be taken in the conditions like
Velcade 3.5mg leads to peripheral neuropathy like burning sensation, hyperesthesia, hypoesthesia, paresthesia, neuropathic pain
Manage postural Hypotension by altering the antihypertensive agents, hydration, and administration of mineralocorticoids or sympathomimetics
Cardiac toxicity :
Pulmonary toxicity like Acute Respiratory Distress Syndrome, pneumonitis, interstitial pneumonia, lung infiltration Posterior reversible encephalopathy syndrome-stop the Velcade 3.5mg therapy
Gastrointestinal toxicity-fluid or electrolyte replacements have to take :
Thrombocytopenia and neutropenia
Tumor lysis syndrome
Hepatic toxicity
Embryo fetal toxicity
SIDE EFFECTS
MOST COMMON SIDE EFFECTS
After administration of Velcade 3.5mg injection Most common side effects are occurred which includes; Black tarry stools ; Bleeding gums ; Blood in urine ; Blurred vision ; Body aches ; Burning, crawling, itching, numbness, prickling ;Chest pain ; Cough producing mucus, dizziness, faintness, nerve pain, painful urination, pale skin, runny nose, sore throat, stuffy nose, swollen glands, sunken eyes, ulcer, dry mouth, ear congestion, loss of voice
LESS COMMON SIDE EFFECTS
loss of appetite, Muscle cramps Belching, bone pain, difficulty with moving & bowel movements, cold and shivering, , loss of taste, , muscle pain, stomach discomfort. Vomiting, loss of weight; irregular breathing , Swelling of peripheral organs ,Dilated veins, discomfort, increased sensitivity of pain & touch, , heart beats, , thickening of bronchial secretions.
PREGNANCY & LACTATION
Velcade 3.5mg is not recommended in pregnancy condition, it causes harm to fetus
Breast feeding is not recommended.
STORAGE
Velcade 3.5mg vial should be stored at 20°C to 25°C (68°F to 77°F) excursion between 15°C to 30°C (59°F to 86°F).
Keep away from light and heat.
CONTACTS DETAILS
Email : millionhealthpharmaceuticals@gmail.com
Phone Number : +91-9940472902
Website : https://millionpharma.com/velcade-3.5mg.php
Velcade 1 mg Injection – Uses, Dosage, Side Effects, Price, Composition|MHP
VELCADE 1MG
DESCRIPTION
Bortezomib is sold under the brand name Velcade 1mg which is a type of anti-cancer medicine, which is in the form of lyophilized powder
A first beneficial proteasome inhibitor is known as Velcade 1mg; proteasome is a cellular structure which breaks the proteins.
Velcade 1mg injection will helps to prevent from multiple myeloma in patients with or without before treatment history and mantle cell lymphoma.
INDICATION
Multiple myeloma :
Velcade 1mg is indicated to treat the patients suffering from multiple myeloma.
Mantle cell lymphoma :
Velcade 1mg is indicated to treat the disease mantle cell lymphoma which the patients have received at least 1 prior therapy.
MECHANISM OF ACTION
Velcade 1mg injection used in mammalian cells is a reversible inhibitor of the chymotrypsin-like activity of the 26-S proteasome. The drug prohibits targeted proteolysis that affects multiple signaling cascades responsible for normal homeostatic functions within the cell, leading to cell death.
PRODUCTS DETAILS
Brand : Velcade
Ingredients : Bortezomib
Strength : 1mg vial
Manufactured : Janssen Pharmaceuticals
Pack : 1mg Bortezomib containing vial in a carton
PHARMACOKINETIC
ABSORPTION
The peak plasma concentration after 1st dose is 57 and 112ng/mL, Ifadministrated two times a week, Cmax observed for 1mg/m2dose is 67 to 106ng/mL, for 1.3mg/m2 is 89 to 720ng/mL.
DISTRIBUTION
human serum plasma concentration is >80%
METABOLISM
Velcade 1mg injection metabolized mainly through cytochrome P450 isoenzymes CYP3A4, CYP2C19 & CYP1A2.
ELIMINATION
The excretion pathways of Velcade have not been characterized.
The terminal elimination of half-life after the 1mg/m2 dose is 40hrs – 193hrs, after dose 1.3mg/m2 is 76hrs – 108hrs.
DOSAGE MANAGEMENT
DOSAGE AND ADMINISTRATION
Velcade is administrated alone or combination with dexamethasone
Three-week course is considered as therapy cycle
At least 72 hours must slip away between constant doses of Velcade
• Velcade (lyophilized powder form) is reconstituted by using 0.9% sodium chloride (NS)
• Velcade should be reconstituted in 3.5ml NS
• The route of administration is IV bolus
• Intrathecal not use for administration
In adults:
MANTLE CELL LYMPHOMA
The Velcade recommended dose for untreated mantle cell lymphoma is;1.3mg/m2 of Velcade administered as IV bolus given as two times weekly by combining with rituximab, cyclophosphamide, doxorubicin and tablet prednisolone for two weeks (day I, IV, VIII & XI) followed rest period of 10 days (day II through 21).
In Relapse stage: The normal dose of Velcade is 1.3mg/m2 administered as IV bolus or subcutaneous two times for two weeks (day I, IV, VIII & XI) followed by 10-day rest period (day II through 21)
The therapy should follow for above 8 cycles may be given for once weekly for 4 weeks (day 1, 8, 15 & 22), followed by 13 day rest (days 23 through 35)
MULTIPLE MYELOMA
In the therapy of previously untreated multiple myeloma:1.3mg/m2 of dose must be given as 3 to 5 seconds through IV bolus or subcutaneous by concomitant use with tablet melphalan and prednisolone for nine 6 weeks therapy cycles
Cycles 1 over 4, Velcade is administrated for two times weekly, (day 1, 4, 8, 11, 22, 25, 29 and 32)
Cycles 5 over 9, Velcade is administrated once a week (day 1, 8, 22, and 29)
KEY POINTS
Moderately, 72 hours should be passing between following doses of Velcade 1mg.
IN RELAPSE STAGE
The usual dose of Velcade is 1.3mg/m2 should be administered through IV bolus or subcutaneous as two times for two weeks (day1, 4, 8, and 11) continued by a ten day of rest course (day 12 through 21) The schedule of the treatment has been raised above 8 cycles may be taken once weekly for 4 weeks (day 1, 8, 15, and 22), followed by 13 day rest (day 23 over 35)
While taking Velcade 1mg some adverse effects occurs care should be taken in the conditions like
Velcade 1mg leads to peripheral neuropathy like burning sensation, hyperesthesia, hypoesthesia, paresthesia, neuropathic pain
Manage postural Hypotension by altering the antihypertensive agents, hydration, and administration of mineralocorticoids or sympathomimetics
Cardiac toxicity :
Pulmonary toxicity like Acute Respiratory Distress Syndrome, pneumonitis, interstitial pneumonia, lung infiltration Posterior reversible encephalopathy syndrome-stop the Velcade 1mg therapy
Gastrointestinal toxicity-fluid or electrolyte replacements have to take :
Thrombocytopenia and neutropenia
Tumor lysis syndrome
Hepatic toxicity
Embryo fetal toxicity
SIDE EFFECTS
MOST COMMON SIDE EFFECTS
After administration of Velcade 1mg injection Most common side effects are occurred which includes; Black tarry stools ; Bleeding gums ; Blood in urine ; Blurred vision ; Body aches ; Burning, crawling, itching, numbness, prickling ;Chest pain ; Cough producing mucus, dizziness, faintness, nerve pain, painful urination, pale skin, runny nose, sore throat, stuffy nose, swollen glands, sunken eyes, ulcer, dry mouth, ear congestion, loss of voice
LESS COMMON SIDE EFFECTS
loss of appetite, Muscle cramps Belching, bone pain, difficulty with moving & bowel movements, cold and shivering, , loss of taste, , muscle pain, stomach discomfort. Vomiting, loss of weight; irregular breathing , Swelling of peripheral organs ,Dilated veins, discomfort, increased sensitivity of pain & touch, , heart beats, , thickening of bronchial secretions
PREGNANCY & LACTATION
Velcade 1mg is not recommended in pregnancy condition, it causes harm to fetus
Breast feeding is not recommended.
STORAGE
Velcade 1mg injection should be stored at 20°C to 25°C (68°F to 77°F) excursion between 15°C to 30°C (59°F to 86°F).
Keep away from light and heat.
CONTACT DETAILS
Email : millionhealthpharmaceuticals@gmail.com
Phone Number : +91-9940472902
Website : https://millionpharma.com/velcade-1mg.php
Sorafenat (sorafenib)|Natco|Anti Cancer Drugs|price in india
SORAFENAT
DESCRIPTION
Sorafenib sold under the brand name Sorafenat 200mg. Sorafenat 200mg Tablets belongs to the group of tyrosine kinase inhibitor or inhibitor of angiogensis. The drug is a type of targeted therapy Sorafenat 200mg is a prescription drug used under the supervision of health care provider.
INDICATION
Sorafenat 200mg Tablets is a anticancer drug and indicated for the treatment of some condition as Advanced renal cell carcinoma Hepatocellular carcinoma Metastatic thyroid carcinoma.
IN RENAL CELL CARCINOMA
The dose of Sorafenat 200mg is given as 400mg should be taken orally as twice daily for at least one hour before or two hours after the meal
THYROID CARCINOMA
The dose of Sorafenat 200mg tablets is given as 400mg should be taken orally as twice daily for at least one hour before or two hours after the meal
HEPATOCELLULAR CARCINOMA
The usual dose of Sorafenat 200mg is given as 400mg should be taken orally as twice daily for at least one hour before or two hours after the meal.
SORAFENAT WORKS IN THE BODY
Sorafenat 200mg includes in deficiency of tumor cell multiplication Sorafenat 200mg interfere with multiple intracellular and cell surface kinase These enzymes are specific for tumor cell signaling, angiogenesis and apoptosis.Sorafenat 200mg Tablets causes to reduce the blood flow to the cancer cells By prohibiting these enzymes (kinase), genetic transcription includes in cell proliferation and angiogenesis is blocked.
DRUG INTERACTION
Interaction of Sorafenat 200mg with Rifampin a strong CYP3A4 inducer, administered at a dose of 600mg single use for 5 days with Sorafenat 200mg Tablets causes decrease AUC of Sorafenib 200mg Interaction with neomycin will reduce the AUC of Sorafenib 200mg Tablets Interaction with acetaminophen will raises the hepatoxicity effect of Sorafenib 200mg Interaction with Bevacizumab will increase the toxic effect of Sorafenib 200mg Tablets
PRODUCTS DETAILS
Brand : Sorafenat Ingredients : Sorafenib
Strength : 200mg
Manufactured : Natco
Package : 120 Tablets
BODY WORKS FOR THE DRUG SORAFENIB
ABSORPTION
The Sorafenat 200mg bioavailability is 38 to 49% The time to peak serum concentration in 3 hours. High fat meals may decrease the bioavailability of Sorafenib
DISTRIBUTION
The drug Sorafenat has Human plasma protein bound is 99.5%
METABOLISM
In liver Sorafenat 200mg Tablets is highly metabolized, it go through oxidative metabolism with the help of CYP3A4 and Glucuronidation by UGT1A9 The main flowing metabolite in serum is pyridine N oxide
ELIMINATION
The dose excreted via feces 77% The dose excreted via urine 19% as glucuronidated metabolites Sorafenat 200mg half life is 25 to 48 hours
SAFETY PRECAUTIONS &
CONTRAINDICATION
Sorafenat 200mg Tablets should not be used, in case of lung cancer, being treated with platinum containing chemo drugs and taxol drugs Sorafenatable to cause heart problems, stop the medicine in case of dizziness, fainting, sweating or shortening of breath Sorafenat causes severe bleeding; care should be taken while getting Sorafenat 200mg Stop the Tablet Sorafenat 200mg in case of;
blood in urine or stools, blood while coughing, Vaginal bleeding Hemorrhage risk QT prolongation. High occurrence of skin toxicity and rashes. Impairs exogenous thyroid suppression. Hypersentivity to the drug and any product of expicients.
SIDE EFFECT
Lymphopenia Neutropenia Hemorrhage Hypertension Neuropathy Anorexia Headache Joint pain Congestive heart failure Acute renal failure Angiodema arrhythmia Interstitial lung disease Post marketing reports: Hypersensitivity reactions: angioedema, anaphylactic reaction Hepatobiliary disorders: hepatitis, hepatic failure and death Musculoskeletal: rhabdomyolysis, osteonecrosis of the jaw Pulmonary: interstitial lung disease
PREGNANCY
Category D: Sorafenat 200mg Tablets can harm to an fetus and cause injury and even death to the unborn baby if you treatment during the 2nd and 3rd trimesters of pregnancy, pregnant women do not use the Sorafenat 200mg medicine without the knowledge of your doctor.
LACTATION
The medicine passes into breast milk is not known or could harm a new born baby. Do not use Sorafenat 200mg Tablets medication, if your breast feeding.
STORAGE
Sorafenat 200mg should be store at 25°C (77°F); excursion are allowed between 15°C and 30oC (59°F and 86°F) Protect from moisture, heat and light
MISSED DOSE
If patient missed to take Sorafenat 200mg Tablets , they may get advice from medical practitioner (consult) for administration of the missed dose within the time Or the missed dose should be skipped and follow the next dosing schedule Do not have double the dose.
CONTACT DETAILS
Email : millionhealthpharmaceuticals@gmail.com
Phone Number : +91-9940472902
Website : https://millionpharma.com/sorafenat.php
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